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The penalties for selling or trading of the suspended products included a fine of P2 million for the first offense, P4 million for the second offense, and P5 million and cancellation of licenses for the third offense

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As between-study heterogeneity can be underestimated or even zero when the number of studies is small 196,197 , we used Fishers information matrix to estimate the uncertainty of the heterogeneity 198 and incorporated that uncertainty into the final results